Targeted Adenoviral Vector Demonstrates Enhanced Efficacy for In Vivo Gene Therapy of Uterine Leiomyoma

BACKGROUND: Gene therapy is a potentially effective non-surgical approach for the treatment of uterine leiomyoma. We demonstrated that targeted adenovirus vector, Ad-SSTR-RGD-TK/GCV, was highly effective in selectively inducing apoptosis and inhibiting proliferation of human leiomyoma cells in vitro...

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Detalhes bibliográficos
Publicado no:Reprod Sci
Main Authors: Abdelaziz, Mohamed, Sherif, Lotfy, ElKhiary, Mostafa, Nair, Sanjeeta, Shalaby, Shahinaz, Mohamed, Sara, Eziba, Noura, El-Lakany, Mohamed, Curiel, David, Ismail, Nahed, Diamond, Michael P., Al-Hendy, Ayman
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2016
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5933189/
https://ncbi.nlm.nih.gov/pubmed/26884457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1933719116630413
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