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Sex-Specific Changes in Renal Angiotensin-Converting Enzyme and Angiotensin-Converting Enzyme 2 Gene Expression and Enzyme Activity at Birth and Over the First Year of Life

OBJECTIVE: Angiotensin-converting enzyme (ACE) and angiotensin-converting enzyme 2 (ACE2) are key enzymes of the renin–angiotensin system. We investigated developmental changes in renal ACE and ACE2 gene expression and activity in both male and female sheep. METHODS: Three groups of sheep (fetus, ne...

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Detalhes bibliográficos
Publicado no:Reprod Sci
Main Authors: Chen, Kai, Bi, Jianli, Su, Yixin, Chappell, Mark C., Rose, James C.
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5933173/
https://ncbi.nlm.nih.gov/pubmed/26243544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1933719115597760
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