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The Nrf2 Activator Vinylsulfone Reduces High Glucose-Induced Neural Tube Defects by Suppressing Cellular Stress and Apoptosis

The nuclear factor erythroid 2-related factor 2 (Nrf2) signaling pathway is one of the primary pathways responsible for the cellular defense system against oxidative stress. Oxidative stress-induced apoptosis is a causal event in diabetic embryopathy. Thus, the Nrf2 pathway may play an important rol...

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Bibliografiske detaljer
Udgivet i:Reprod Sci
Main Authors: Dong, Daoyin, Reece, E. Albert, Yang, Peixin
Format: Artigo
Sprog:Inglês
Udgivet: SAGE Publications 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5933102/
https://ncbi.nlm.nih.gov/pubmed/26802109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1933719115625846
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