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Deconvolution of Voltage Sensor Time Series and Electro-diffusion Modeling Reveal the Role of Spine Geometry in Controlling Synaptic Strength

Most synaptic excitatory connections are made on dendritic spines. But how the voltage in spines is modulated by its geometry remains unclear. To investigate the electrical properties of spines, we combine voltage imaging data with electro-diffusion modeling. We first present a temporal deconvolutio...

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Publicado en:Neuron
Autores principales: Cartailler, Jerome, Kwon, Taekyung, Yuste, Rafael, Holcman, David
Formato: Artigo
Lenguaje:Inglês
Publicado: 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5933057/
https://ncbi.nlm.nih.gov/pubmed/29429935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2018.01.034
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