VISTA expression associated with CD8 confers a favorable immune microenvironment and better overall survival in hepatocellular carcinoma

BACKGROUND: Hepatocellular carcinoma (HCC) often arises in the setting of chronic inflammation with multiple inhibitory immune signals. V-domain Ig suppressor of T cell activation (VISTA) is identified as a novel negative checkpoint regulator. This study sought to determine the expression and progno...

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Gepubliceerd in:BMC Cancer
Hoofdauteurs: Zhang, Ming, Pang, Hua-Jin, Zhao, Wei, Li, Yu-Fa, Yan, Li-Xu, Dong, Zhong-Yi, He, Xiao-Feng
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2018
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5932869/
https://ncbi.nlm.nih.gov/pubmed/29720116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-018-4435-1
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