Mesenchymal stem cells attenuate blood-brain barrier leakage after cerebral ischemia in mice

BACKGROUND: Ischemic stroke induced matrixmetallo-proteinase-9 (MMP-9) upregulation, which increased blood-brain barrier permeability. Studies demonstrated that mesenchymal stem cell therapy protected blood-brain barrier disruption from several cerebrovascular diseases. However, the underlying mecha...

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Bibliographic Details
Published in:J Neuroinflammation
Main Authors: Cheng, Zhuo, Wang, Liping, Qu, Meijie, Liang, Huaibin, Li, Wanlu, Li, Yongfang, Deng, Lidong, Zhang, Zhijun, Yang, Guo-Yuan
Format: Artigo
Language:Inglês
Published: BioMed Central 2018
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5932816/
https://ncbi.nlm.nih.gov/pubmed/29724240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-018-1153-1
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