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Outcome pre-specification requires sufficient detail to guard against outcome switching in clinical trials: a case study
BACKGROUND: Pre-specification of outcomes is an important tool to guard against outcome switching in clinical trials. However, if the outcome is not sufficiently clearly defined, then different definitions could be applied and analysed, with only the most favourable result reported. METHODS: In orde...
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| Pubblicato in: | Trials |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5932799/ https://ncbi.nlm.nih.gov/pubmed/29720248 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13063-018-2654-z |
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