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Identification of a selective DNA ligase for accurate recognition and ultrasensitive quantification of N(6)-methyladenosine in RNA at one-nucleotide resolution
N (6)-Methyladenosine (m(6)A) is the most frequent post-transcriptional modification in RNA, and it plays a critical role in biological processes. The functions of m(6)A remain largely unexplored due to a lack of highly sensitive methods to quantitatively determine the m(6)A modification fraction at...
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| Publicado no: | Chem Sci |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Royal Society of Chemistry
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5932600/ https://ncbi.nlm.nih.gov/pubmed/29780465 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7sc05233b |
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