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Genetics of Amyotrophic Lateral Sclerosis

Amyotrophic lateral sclerosis (ALS) is a devastating, uniformly lethal degenerative disorder of motor neurons that overlaps clinically with frontotemporal dementia (FTD). Investigations of the 10% of ALS cases that are transmitted as dominant traits have revealed numerous gene mutations and variants...

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Detalhes bibliográficos
Publicado no:Cold Spring Harb Perspect Med
Main Authors: Ghasemi, Mehdi, Brown, Robert H.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5932579/
https://ncbi.nlm.nih.gov/pubmed/28270533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a024125
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