Leveraging lung tissue transcriptome to uncover candidate causal genes in COPD genetic associations

Causal genes of chronic obstructive pulmonary disease (COPD) remain elusive. The current study aims at integrating genome-wide association studies (GWAS) and lung expression quantitative trait loci (eQTL) data to map COPD candidate causal genes and gain biological insights into the recently discover...

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Detalhes bibliográficos
Publicado no:Hum Mol Genet
Main Authors: Lamontagne, Maxime, Bérubé, Jean-Christophe, Obeidat, Ma’en, Cho, Michael H, Hobbs, Brian D, Sakornsakolpat, Phuwanat, de Jong, Kim, Boezen, H Marike, Nickle, David, Hao, Ke, Timens, Wim, van den Berge, Maarten, Joubert, Philippe, Laviolette, Michel, Sin, Don D, Paré, Peter D, Bossé, Yohan
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Association Studies Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5932553/
https://ncbi.nlm.nih.gov/pubmed/29547942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddy091
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