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Stabilization of Urinary MicroRNAs by Association with Exosomes and Argonaute 2 Protein

A pressing need for new chronic kidney disease (CKD) biomarkers persists. MicroRNAs (miRNAs) are emerging as a novel class of disease biomarkers in body fluids, but mechanisms conferring their stability in urine have not been fully elucidated. Here we investigated stabilization in human urine of ubi...

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Vydáno v:Noncoding RNA
Hlavní autoři: Beltrami, Cristina, Clayton, Aled, Newbury, Lucy J., Corish, Peter, Jenkins, Robert H., Phillips, Aled O., Fraser, Donald J., Bowen, Timothy
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5932545/
https://ncbi.nlm.nih.gov/pubmed/29861421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ncrna1020151
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