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MicroRNA Silencing by DNA Methylation in Human Cancer: a Literature Analysis

MicroRNAs (miRNAs) are small non-coding RNAs that post-transcriptionally regulate the expression of target mRNAs. MicroRNA genes themselves are regulated through epigenetic mechanisms, such as histone modifications and/or DNA methylation of CpG islands. Aberrant CpG island methylation patterns are f...

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Detalhes bibliográficos
Publicado no:Noncoding RNA
Main Authors: Strmsek, Ziga, Kunej, Tanja
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5932538/
https://ncbi.nlm.nih.gov/pubmed/29861414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ncrna1010044
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