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Myosin VI-Dependent Actin Cages Encapsulate Parkin-Positive Damaged Mitochondria

Mitochondrial quality control is essential to maintain cellular homeostasis and is achieved by removing damaged, ubiquitinated mitochondria via Parkin-mediated mitophagy. Here, we demonstrate that MYO6 (myosin VI), a unique myosin that moves toward the minus end of actin filaments, forms a complex w...

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Detalhes bibliográficos
Publicado no:Dev Cell
Main Authors: Kruppa, Antonina J., Kishi-Itakura, Chieko, Masters, Thomas A., Rorbach, Joanna E., Grice, Guinevere L., Kendrick-Jones, John, Nathan, James A., Minczuk, Michal, Buss, Folma
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5932465/
https://ncbi.nlm.nih.gov/pubmed/29398621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2018.01.007
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