Voltage Gated Calcium Channel Activation by Backpropagating Action Potentials Downregulates NMDAR Function

The majority of excitatory synapses are located on dendritic spines of cortical glutamatergic neurons. In spines, compartmentalized Ca(2+) signals transduce electrical activity into specific long-term biochemical and structural changes. Action potentials (APs) propagate back into the dendritic tree...

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Detalles Bibliográficos
Publicado en:Front Cell Neurosci
Main Authors: Theis, Anne-Kathrin, Rózsa, Balázs, Katona, Gergely, Schmitz, Dietmar, Johenning, Friedrich W.
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2018
Assuntos:
Neuroscience
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5932410/
https://ncbi.nlm.nih.gov/pubmed/29755321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2018.00109
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