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Genetic hitchhiking and population bottlenecks contribute to prostate cancer disparities in men of African descent

Prostate cancer (CaP) incidence and mortality rates in African and African American men are greatly elevated compared to other ethnicities. This disparity is likely explained by a combination of social, environmental, and genetic factors. A large number of susceptibility loci have been reported by g...

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Publicado en:Cancer Res
Autores principales: Lachance, Joseph, Berens, Ali J., Hansen, Matthew E. B., Teng, Andrew K., Tishkoff, Sarah A., Rebbeck, Timothy R.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5932264/
https://ncbi.nlm.nih.gov/pubmed/29438991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-17-1550
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