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Stability and anti-inflammatory activity of the reduction-resistant curcumin analog, 2,6-dimethyl-curcumin

The efficacy of the curry spice compound curcumin as a natural anti-inflammatory agent is limited by its rapid reductive metabolism in vivo. A recent report described a novel synthetic derivative, 2,6-dimethyl-curcumin, with increased stability against reduction in vitro and in vivo. It is also know...

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Detalhes bibliográficos
Publicado no:Org Biomol Chem
Main Authors: Joseph, Akil I., Edwards, Rebecca L., Luis, Paula B., Presley, Sai Han, Porter, Ned A., Schneider, Claus
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5932260/
https://ncbi.nlm.nih.gov/pubmed/29664496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8ob00639c
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