Human Papillomavirus DNA methylation as a biomarker for cervical precancer: Consistency across 12 genotypes and potential impact on management of HPV-positive women

PURPOSE: Human papillomavirus (HPV) DNA methylation testing is a promising triage option for women testing HPV-positive during cervical cancer screening. However, the extent to which methylation indicates precancer for all 12 carcinogenic HPV types has not been evaluated. METHODS: In this nested cas...

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Pubblicato in:Clin Cancer Res
Autori principali: Clarke, Megan A., Gradissimo, Ana, Schiffman, Mark, Lam, Jessica, Sollecito, Christopher C., Fetterman, Barbara, Lorey, Thomas, Poitras, Nancy, Raine-Bennett, Tina R., Castle, Philip E., Wentzensen, Nicolas, Burk, Robert D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5932258/
https://ncbi.nlm.nih.gov/pubmed/29420222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-17-3251
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