Immune Response Generated With the Administration of Autologous Dendritic Cells Pulsed With an Allogenic Tumoral Cell-Lines Lysate in Patients With Newly Diagnosed Diffuse Intrinsic Pontine Glioma

BACKGROUND AND OBJECTIVE: Diffuse intrinsic pontine glioma (DIPG) is a lethal brainstem tumor in children. Dendritic cells (DCs) have T-cell stimulatory capacity and, therefore, potential antitumor activity for disease control. DCs vaccines have been shown to reactivate tumor-specific T cells in bot...

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Udgivet i:Front Oncol
Main Authors: Benitez-Ribas, Daniel, Cabezón, Raquel, Flórez-Grau, Georgina, Molero, Mari Carmen, Puerta, Patricia, Guillen, Antonio, González-Navarro, E. Azucena, Paco, Sonia, Carcaboso, Angel M., Santa-Maria Lopez, Vicente, Cruz, Ofelia, de Torres, Carmen, Salvador, Noelia, Juan, Manel, Mora, Jaume, La Madrid, Andres Morales
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2018
Fag:
Oncology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5932163/
https://ncbi.nlm.nih.gov/pubmed/29755954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2018.00127
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