Caspase-3 Inhibition Attenuates the Cytopathic Effects of EV71 Infection

Previous studies demonstrate that human enterovirus 71 (EV71), a primary causative agent for hand, foot, and mouth disease, activates caspase-3 through the non-structural viral 3C protein to induce host cell apoptosis; however, until now it was unclear how 3C activates caspase-3 and how caspase-3 ac...

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Detalles Bibliográficos
Publicado en:Front Microbiol
Autores principales: Song, Fengmei, Yu, Xiaoyan, Zhong, Ting, Wang, Zengyan, Meng, Xiangling, Li, Zhaolong, Zhang, Shuxia, Huo, Wenbo, Liu, Xin, Zhang, Yahong, Zhang, Wenyan, Yu, Jinghua
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2018
Materias:
Microbiology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5932146/
https://ncbi.nlm.nih.gov/pubmed/29755438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2018.00817
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