CE-BLAST makes it possible to compute antigenic similarity for newly emerging pathogens

Major challenges in vaccine development include rapidly selecting or designing immunogens for raising cross-protective immunity against different intra- or inter-subtypic pathogens, especially for the newly emerging varieties. Here we propose a computational method, Conformational Epitope (CE)-BLAST...

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Udgivet i:Nat Commun
Main Authors: Qiu, Tianyi, Yang, Yiyan, Qiu, Jingxuan, Huang, Yang, Xu, Tianlei, Xiao, Han, Wu, Dingfeng, Zhang, Qingchen, Zhou, Chen, Zhang, Xiaoyan, Tang, Kailin, Xu, Jianqing, Cao, Zhiwei
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5932059/
https://ncbi.nlm.nih.gov/pubmed/29720583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-04171-2
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