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Crystal structure of intraflagellar transport protein 80 reveals a homo-dimer required for ciliogenesis

Oligomeric assemblies of intraflagellar transport (IFT) particles build cilia through sequential recruitment and transport of ciliary cargo proteins within cilia. Here we present the 1.8 Å resolution crystal structure of the Chlamydomonas IFT-B protein IFT80, which reveals the architecture of two N-...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Taschner, Michael, Lorentzen, Anna, Mourão, André, Collins, Toby, Freke, Grace M, Moulding, Dale, Basquin, Jerome, Jenkins, Dagan, Lorentzen, Esben
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5931796/
https://ncbi.nlm.nih.gov/pubmed/29658880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.33067
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