Weighted Multi-marker Genetic Risk Scores for Incident Coronary Heart Disease among Individuals of African, Latino and East-Asian Ancestry

We examined the clinical utility of two multi-locus genetic risk scores (GRSs) previously validated in Europeans among persons of African (AFR; n = 2,089), Latino (LAT; n = 4,349) and East-Asian (EA; n = 4,804) ancestry. We used data from the GERA cohort (30–79 years old, 68 to 73% female). We utili...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Iribarren, Carlos, Lu, Meng, Jorgenson, Eric, Martínez, Manuel, Lluis-Ganella, Carla, Subirana, Isaac, Salas, Eduardo, Elosua, Roberto
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5931622/
https://ncbi.nlm.nih.gov/pubmed/29717161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-25128-x
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