Effective in vivo treatment of acute lung injury with helical, amphipathic peptoid mimics of pulmonary surfactant proteins

Acute lung injury (ALI) leads to progressive loss of breathing capacity and hypoxemia, as well as pulmonary surfactant dysfunction. ALI’s pathogenesis and management are complex, and it is a significant cause of morbidity and mortality worldwide. Exogenous surfactant therapy, even for research purpo...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Czyzewski, Ann M., McCaig, Lynda M., Dohm, Michelle T., Broering, Lauren A., Yao, Li-Juan, Brown, Nathan J., Didwania, Maruti K., Lin, Jennifer S., Lewis, Jim F., Veldhuizen, Ruud, Barron, Annelise E.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5931611/
https://ncbi.nlm.nih.gov/pubmed/29717157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-25009-3
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