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Scope and limitations of carbohydrate hydrolysis for de novo glycan sequencing using a hydrogen peroxide/metallopeptide-based glycosidase mimetic

Acidic hydrolysis is commonly used as a first step to break down oligo- and polysaccharides into monosaccharide units for structural analysis. While easy to set up and amenable to mass spectrometry detection, acid hydrolysis is not without its drawbacks. For example, ring-destruction side reactions...

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Detalhes bibliográficos
Publicado no:Carbohydr Res
Main Authors: Peng, Tianyuan, Wooke, Zachary, Pohl, Nicola L. B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5931371/
https://ncbi.nlm.nih.gov/pubmed/29475194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.carres.2018.01.008
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