Targeting the gut microbiome to treat the osteoarthritis of obesity

Obesity is a risk factor for osteoarthritis (OA), the greatest cause of disability in the US. The impact of obesity on OA is driven by systemic inflammation, and increased systemic inflammation is now understood to be caused by gut microbiome dysbiosis. Oligofructose, a nondigestible prebiotic fiber...

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Veröffentlicht in:JCI Insight
Hauptverfasser: Schott, Eric M., Farnsworth, Christopher W., Grier, Alex, Lillis, Jacquelyn A., Soniwala, Sarah, Dadourian, Gregory H., Bell, Richard D., Doolittle, Madison L., Villani, David A., Awad, Hani, Ketz, John P., Kamal, Fadia, Ackert-Bicknell, Cheryl, Ashton, John M., Gill, Steven R., Mooney, Robert A., Zuscik, Michael J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2018
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5931133/
https://ncbi.nlm.nih.gov/pubmed/29669931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.95997
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