Global Identification of Small Ubiquitin-related Modifier (SUMO) Substrates Reveals Crosstalk between SUMOylation and Phosphorylation Promotes Cell Migration

Proteomics studies have revealed that SUMOylation is a widely used post-translational modification (PTM) in eukaryotes. However, how SUMO E1/2/3 complexes use different SUMO isoforms and recognize substrates remains largely unknown. Using a human proteome microarray-based activity screen, we identif...

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Vydáno v:Mol Cell Proteomics
Hlavní autoři: Uzoma, Ijeoma, Hu, Jianfei, Cox, Eric, Xia, Shuli, Zhou, Jianying, Rho, Hee-Sool, Guzzo, Catherine, Paul, Corry, Ajala, Olutobi, Goodwin, C. Rory, Jeong, Junseop, Moore, Cedric, Zhang, Hui, Meluh, Pamela, Blackshaw, Seth, Matunis, Michael, Qian, Jiang, Zhu, Heng
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Biochemistry and Molecular Biology 2018
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5930406/
https://ncbi.nlm.nih.gov/pubmed/29438996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.RA117.000014
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