Bacteroides thetaiotaomicron generates diverse α-mannosidase activities through subtle evolution of a distal substrate-binding motif

A dominant human gut microbe, the well studied symbiont Bacteroides thetaiotaomicron (Bt), is a glyco-specialist that harbors a large repertoire of genes devoted to carbohydrate processing. Despite strong similarities among them, many of the encoded enzymes have evolved distinct substrate specificit...

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Detalhes bibliográficos
Publicado no:Acta Crystallogr D Struct Biol
Main Authors: Thompson, Andrew J., Spears, Richard J., Zhu, Yanping, Suits, Michael D. L., Williams, Spencer J., Gilbert, Harry J., Davies, Gideon J.
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2018
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5930347/
https://ncbi.nlm.nih.gov/pubmed/29717710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2059798318002942
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