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Evaluation of the systemic toxicity and mutagenicity of OLIGOPIN®, procyanidolic oligomers (OPC) extracted from French Maritime Pine Bark extract

The potential systemic toxicity of Oligopin®, a French Maritime Pine Bark extract (FMPBE) rich in procyanidolic oligomers, was evaluated in an acute oral limit test and a 90-day repeated dose oral toxicity study with Sprague Dawley rats. The potential mutagenicity was assessed in a bacterial reverse...

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Detalhes bibliográficos
Publicado no:Toxicol Rep
Main Authors: Segal, L, Penman, MG, Piriou, Y
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5930179/
https://ncbi.nlm.nih.gov/pubmed/29725583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.toxrep.2018.03.013
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