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Sirtuin 1-chromatin-binding dynamics points to a common mechanism regulating inflammatory targets in SIV infection and in the aging brain

Microglia and macrophages are the main non-neuronal subsets of myeloid origin in the brain, and are critical regulators in neurodegenerative disorders, where inflammation is a key factor. Since HIV infection results in neurological perturbations that are similar to those in aging, we examined microg...

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Bibliographische Detailangaben
Veröffentlicht in:J Neuroimmune Pharmacol
Hauptverfasser: Bortell, Nikki, Basova, Liana, Najera, Julia A., Morsey, Brenda, Fox, Howard S., Marcondes, Maria Cecilia Garibaldi
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5930062/
https://ncbi.nlm.nih.gov/pubmed/29280055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11481-017-9772-3
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