Sedative Plasma Concentrations and Delirium Risk in Critical Illness

BACKGROUND: The relationship between plasma concentration of sedatives and delirium is unknown. OBJECTIVE: We hypothesized that higher plasma concentrations of lorazepam are associated with increased delirium risk, whereas higher plasma concentrations of dexmedetomidine are associated with reduced d...

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Veröffentlicht in:Ann Pharmacother
Hauptverfasser: Stollings, Joanna L., Thompson, Jennifer L., Ferrell, Benjamin A., Scheinin, Mika, Wilkinson, Grant R., Hughes, Christopher G., Shintani, Ayumi K., Ely, E. Wesley, Girard, Timothy D., Pandharipande, Pratik P., Patel, Mayur B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5930024/
https://ncbi.nlm.nih.gov/pubmed/29363356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1060028017753480
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