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Galectin-9 modulates immunity by promoting Th2/M2 differentiation and impacts survival in patients with metastatic melanoma
PURPOSE: Galectin-9, a β-galactoside binding protein, is defined as a negative regulator of T helper 1 (Th1) immune responses, favoring Th2 bias. Systemic immunity in patients with metastatic melanoma is predominately Th2 biased. We hypothesized galectin-9 could modulate systemic immunity toward Th2...
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| Publicado en: | Melanoma Res |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5929986/ https://ncbi.nlm.nih.gov/pubmed/27455380 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CMR.0000000000000281 |
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