Determination of Autoantibody Isotypes Increases the Sensitivity of Serodiagnostics in Rheumatoid Arthritis

Anti-citrullinated protein antibodies (ACPA) and rheumatoid factor (RF) are the most commonly used diagnostic markers of rheumatoid arthritis (RA). These antibodies are predominantly of the immunoglobulin (Ig) M (RF) or IgG (ACPA) isotype. Other subtypes of both antibodies—particularly IgA isotypes...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Sieghart, Daniela, Platzer, Alexander, Studenic, Paul, Alasti, Farideh, Grundhuber, Maresa, Swiniarski, Sascha, Horn, Thomas, Haslacher, Helmuth, Blüml, Stephan, Smolen, Josef, Steiner, Günter
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5929149/
https://ncbi.nlm.nih.gov/pubmed/29740454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00876
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