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The Oxidation State of [4Fe4S] Clusters Modulates the DNA-Binding Affinity of DNA Repair Proteins

A central question important to understanding DNA repair is how certain proteins are able to search for, detect, and fix DNA damage on a biologically relevant timescale. A feature of many base excision repair proteins is that they contain [4Fe4S] clusters that may aid their search for lesions. In th...

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Détails bibliographiques
Publié dans:J Am Chem Soc
Auteurs principaux: Tse, Edmund C. M., Zwang, Theodore J., Barton, Jacqueline K.
Format: Artigo
Langue:Inglês
Publié: 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5929122/
https://ncbi.nlm.nih.gov/pubmed/28817778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.7b07230
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