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Polyamine-Targeting Gefitinib Prodrug and its Near-Infrared Fluorescent Theranostic Derivative for Monitoring Drug Delivery and Lung Cancer Therapy

The therapy of non-small-cell lung cancer (NSCLC) is challenging because of poor prognosis. There are urgent demands for targeting anti-tumor drugs with reliable efficacy and clear pharmacokinetics. Methods: We designed and synthesized an active tumor-targeting prodrug for the precision therapy of N...

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Dades bibliogràfiques
Publicat a:Theranostics
Autors principals: Song, Xinyu, Han, Xiaoyue, Yu, Fabiao, Zhang, Xiaoyu, Chen, Lingxin, Lv, Changjun
Format: Artigo
Idioma:Inglês
Publicat: Ivyspring International Publisher 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5928882/
https://ncbi.nlm.nih.gov/pubmed/29721074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.24041
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