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Development of a novel albumin-based and maleimidopropionic acid-conjugated peptide with prolonged half-life and increased in vivo anti-tumor efficacy

Angiogenesis plays a critical role in tumor aggressiveness, and a lot of anti-angiogenic agents have been used in clinical therapy. The therapeutic efficacy of peptides are generally restricted by the short in vivo life-time, thus, we were interested in developing a novel albumin-based and maleimido...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Theranostics
Hauptverfasser: Feng, Junnan, Zhao, Chuanke, Wang, Lixin, Qu, Like, Zhu, Hua, Yang, Zhi, An, Guo, Tian, Huifang, Shou, Chengchao
Format: Artigo
Sprache:Inglês
Veröffentlicht: Ivyspring International Publisher 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5928873/
https://ncbi.nlm.nih.gov/pubmed/29721065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.22069
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