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Development of a novel albumin-based and maleimidopropionic acid-conjugated peptide with prolonged half-life and increased in vivo anti-tumor efficacy

Angiogenesis plays a critical role in tumor aggressiveness, and a lot of anti-angiogenic agents have been used in clinical therapy. The therapeutic efficacy of peptides are generally restricted by the short in vivo life-time, thus, we were interested in developing a novel albumin-based and maleimido...

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Detalhes bibliográficos
Publicado no:Theranostics
Main Authors: Feng, Junnan, Zhao, Chuanke, Wang, Lixin, Qu, Like, Zhu, Hua, Yang, Zhi, An, Guo, Tian, Huifang, Shou, Chengchao
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5928873/
https://ncbi.nlm.nih.gov/pubmed/29721065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.22069
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