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Exosomal Tat protein activates latent HIV-1 in primary, resting CD4(+) T lymphocytes
Replication competent HIV-1 persists in a subpopulation of CD4(+) T lymphocytes despite prolonged antiretroviral treatment. This residual reservoir of infected cells harbors transcriptionally silent provirus capable of reigniting productive infection upon discontinuation of antiretroviral therapy. C...
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| Publicado no: | JCI Insight |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5928859/ https://ncbi.nlm.nih.gov/pubmed/29618654 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.95676 |
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