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Ontogeny and reversal of brain circuit abnormalities in a preclinical model of PCOS

Androgen excess is a hallmark of polycystic ovary syndrome (PCOS), a prevalent yet poorly understood endocrine disorder. Evidence from women and preclinical animal models suggests that elevated perinatal androgens can elicit PCOS onset in adulthood, implying androgen actions in both PCOS ontogeny an...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Silva, Mauro S.B., Prescott, Melanie, Campbell, Rebecca E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5928858/
https://ncbi.nlm.nih.gov/pubmed/29618656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.99405
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