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Ontogeny and reversal of brain circuit abnormalities in a preclinical model of PCOS

Androgen excess is a hallmark of polycystic ovary syndrome (PCOS), a prevalent yet poorly understood endocrine disorder. Evidence from women and preclinical animal models suggests that elevated perinatal androgens can elicit PCOS onset in adulthood, implying androgen actions in both PCOS ontogeny an...

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Bibliographische Detailangaben
Veröffentlicht in:JCI Insight
Hauptverfasser: Silva, Mauro S.B., Prescott, Melanie, Campbell, Rebecca E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5928858/
https://ncbi.nlm.nih.gov/pubmed/29618656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.99405
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