ICAM3 mediates inflammatory signaling to promote cancer cell stemness

In this study, we present a medium throughput siRNA screen platform to identify inflammation genes that regulate cancer cell stemness. We identified several novel candidates that decrease OCT4 expression and reduce the ALDH+ subpopulation both of which are characteristic of stemness. Furthermore, on...

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Vydáno v:Cancer Lett
Hlavní autoři: Shen, Wenzhi, Xie, Junling, Zhao, Shuangtao, Du, Renle, Luo, Xiaohe, He, Huiwen, Jiang, Shan, Hao, Na, Chen, Chong, Guo, Chunlei, Liu, Yanhua, Chen, Yanan, Sun, Peiqing, Yang, Shengyong, Luo, Na, Xiang, Rong, Luo, Yunping
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5928798/
https://ncbi.nlm.nih.gov/pubmed/29477378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2018.02.034
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