Metabolomics-based discovery of a metabolite that enhances oligodendrocyte maturation

Endogenous metabolites play essential roles in the regulation of cellular identity and activity. Here we have investigated the process of oligodendrocyte precursor cell (OPC) differentiation, a process that becomes limiting during progressive stages of demyelinating diseases, including multiple scle...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Chem Biol
Prif Awduron: Beyer, Brittney A, Fang, Mingliang, Sadrian, Benjamin, Montenegro-Burke, J Rafael, Plaisted, Warren C, Kok, Bernard P C, Saez, Enrique, Kondo, Toru, Siuzdak, Gary, Lairson, Luke L
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2017
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5928791/
https://ncbi.nlm.nih.gov/pubmed/29131145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.2517
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