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Sterol uptake and sterol biosynthesis act coordinately to mediate antifungal resistance in Candida glabrata under azole and hypoxic stress

Pathogenic fungi, including Candida glabrata, develop strategies to grow and survive both in vitro and in vivo under azole stress. However, the mechanisms by which yeast cells counteract the inhibitory effects of azoles are not completely understood. In the current study, it was demonstrated that th...

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Pubblicato in:Mol Med Rep
Autori principali: Li, Qingdi Quentin, Tsai, Huei-Fung, Mandal, Ajeet, Walker, Bryan A., Noble, Jason A., Fukuda, Yuichi, Bennett, John E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: D.A. Spandidos 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5928633/
https://ncbi.nlm.nih.gov/pubmed/29532896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2018.8716
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