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Identification of IL-1β and LPS as Optimal Activators of Monolayer and Alginate-Encapsulated Mesenchymal Stromal Cell Immunomodulation Using Design of Experiments and Statistical Methods

Induction of therapeutic mesenchymal stromal cell (MSC) function is dependent upon activating factors present in diseased or injured tissue microenvironments. These functions include modulation of macrophage phenotype via secreted molecules including prostaglandin E2 (PGE2). Many approaches aim to o...

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Dettagli Bibliografici
Pubblicato in:Biotechnol Prog
Autori principali: Gray, Andrea, Maguire, Timothy, Schloss, Rene, Yarmush, Martin L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5928509/
https://ncbi.nlm.nih.gov/pubmed/25958832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/btpr.2103
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