Estrogen Receptor (ER) Subtype Selectivity Identifies 8-Prenylapigenin as an ERβ Agonist from Glycyrrhiza inflata and Highlights the Importance of Chemical and Biological Authentication

[Image: see text] Postmenopausal women are increasingly using botanicals for menopausal symptom relief due to the increased breast cancer risk associated with traditional estrogen therapy. The deleterious effects of estrogens are associated with estrogen receptor (ER)α-dependent proliferation, while...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Nat Prod
Prif Awduron: Hajirahimkhan, Atieh, Mbachu, Obinna, Simmler, Charlotte, Ellis, Sarah G., Dong, Huali, Nikolic, Dejan, Lankin, David C., van Breemen, Richard B., Chen, Shao-Nong, Pauli, Guido F., Dietz, Birgit M., Bolton, Judy L.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Chemical Society and American Society of Pharmacognosy 2018
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5928484/
https://ncbi.nlm.nih.gov/pubmed/29641206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jnatprod.7b01070
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