Atorvastatin pretreatment attenuates kainic acid-induced hippocampal neuronal death via regulation of lipocalin-2-associated neuroinflammation

Statins mediate vascular protection and reduce the prevalence of cardiovascular diseases. Recent work indicates that statins have anticonvulsive effects in the brain; however, little is known about the precise mechanism for its protective effect in kainic acid (KA)-induced seizures. Here, we investi...

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Vydáno v:Korean J Physiol Pharmacol
Hlavní autoři: Jin, Zhen, Jung, Yohan, Yi, Chin-ok, Lee, Jong Youl, Jeong, Eun Ae, Lee, Jung Eun, Park, Ki-Jong, Kwon, Oh-Young, Lim, Byeong Hoon, Choi, Nack-Cheon, Roh, Gu Seob
Médium: Artigo
Jazyk:Inglês
Vydáno: The Korean Physiological Society and The Korean Society of Pharmacology 2018
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5928343/
https://ncbi.nlm.nih.gov/pubmed/29719452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4196/kjpp.2018.22.3.301
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