Increase in Mitochondrial Biogenesis in Neuronal Cells by RNS60, a Physically-Modified Saline, via Phosphatidylinositol 3-Kinase-Mediated Upregulation of PGC1α

This study highlights a novel approach to upregulate mitochondrial biogenesis in neuronal cells. RNS60 is a 0.9% saline solution containing oxygenated nanobubbles that is generated by subjecting normal saline to Taylor-Couette-Poiseuille (TCP) flow under elevated oxygen pressure. RNS60, but not NS (...

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Veröffentlicht in:J Neuroimmune Pharmacol
Hauptverfasser: Chandra, Goutam, Kundu, Madhuchhanda, Rangasamy, Suresh B., Dasarathy, Sridevi, Ghosh, Supurna, Watson, Richard, Pahan, Kalipada
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer US 2017
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5928179/
https://ncbi.nlm.nih.gov/pubmed/29188424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11481-017-9771-4
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