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Challenges of ligand identification for the second wave of orphan riboswitch candidates

Orphan riboswitch candidates are noncoding RNA motifs whose representatives are believed to function as genetic regulatory elements, but whose target ligands have yet to be identified. The study of certain orphans, particularly classes that have resisted experimental validation for many years, has l...

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Bibliografische gegevens
Gepubliceerd in:RNA Biol
Hoofdauteurs: Greenlee, Etienne B., Stav, Shira, Atilho, Ruben M., Brewer, Kenneth I., Harris, Kimberly A., Malkowski, Sarah N., Mirihana Arachchilage, Gayan, Perkins, Kevin R., Sherlock, Madeline E., Breaker, Ronald R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Taylor & Francis 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5927730/
https://ncbi.nlm.nih.gov/pubmed/29135333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2017.1403002
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