Challenges of ligand identification for the second wave of orphan riboswitch candidates

Orphan riboswitch candidates are noncoding RNA motifs whose representatives are believed to function as genetic regulatory elements, but whose target ligands have yet to be identified. The study of certain orphans, particularly classes that have resisted experimental validation for many years, has l...

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Detalhes bibliográficos
Publicado no:RNA Biol
Main Authors: Greenlee, Etienne B., Stav, Shira, Atilho, Ruben M., Brewer, Kenneth I., Harris, Kimberly A., Malkowski, Sarah N., Mirihana Arachchilage, Gayan, Perkins, Kevin R., Sherlock, Madeline E., Breaker, Ronald R.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5927730/
https://ncbi.nlm.nih.gov/pubmed/29135333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2017.1403002
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