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Spurious transcription and its impact on cell function

Most RNA polymerases can initiate transcription from diverse DNA template sequences with relatively few outright sequence restraints. Recent reports have demonstrated that failure to subdue the promiscuity of RNA polymerase in vivo can severely impede cell function. This phenomenon appears common to...

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Publicado no:Transcription
Main Authors: Wade, Joseph T., Grainger, David C.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5927700/
https://ncbi.nlm.nih.gov/pubmed/28980880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21541264.2017.1381794
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