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TNFa and IL-2 armed adenoviruses enable complete responses by anti-PD-1 checkpoint blockade

Releasing the patient's immune system against their own malignancy by the use of checkpoint inhibitors is delivering promising results. However, only a subset of patients currently benefit from them. One major limitation of these therapies relates to the inability of T cells to detect or penetr...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Cervera-Carrascon, V., Siurala, M., Santos, J. M., Havunen, R., Tähtinen, S., Karell, P., Sorsa, S., Kanerva, A., Hemminki, A.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5927535/
https://ncbi.nlm.nih.gov/pubmed/29721366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2017.1412902
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