Viral targeting of TFIIB impairs de novo polymerase II recruitment and affects antiviral immunity

Viruses have evolved a plethora of mechanisms to target host antiviral responses. Here, we propose a yet uncharacterized mechanism of immune regulation by the orthomyxovirus Thogoto virus (THOV) ML protein through engaging general transcription factor TFIIB. ML generates a TFIIB depleted nuclear env...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Haas, Darya A., Meiler, Arno, Geiger, Katharina, Vogt, Carola, Preuss, Ellen, Kochs, Georg, Pichlmair, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5927403/
https://ncbi.nlm.nih.gov/pubmed/29709033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006980
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados