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Viral targeting of TFIIB impairs de novo polymerase II recruitment and affects antiviral immunity
Viruses have evolved a plethora of mechanisms to target host antiviral responses. Here, we propose a yet uncharacterized mechanism of immune regulation by the orthomyxovirus Thogoto virus (THOV) ML protein through engaging general transcription factor TFIIB. ML generates a TFIIB depleted nuclear env...
Shranjeno v:
| izdano v: | PLoS Pathog |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Public Library of Science
2018
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5927403/ https://ncbi.nlm.nih.gov/pubmed/29709033 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006980 |
| Oznake: |
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