Sensitivity of Human Cancer Cells to the New Anticancer Ribo‐nucleoside TAS–106 Is Correlated with Expression of Uridine‐cytidine Kinase 2

TAS–106 [l–(3–C‐ethynyl‐β‐d‐ribo‐pentofuranosyl)cytosine] is a new anticancer ribo‐nucleoside with promising antitumor activity. We have previously presented evidence suggesting that the TAS–106 sensitivity of cells is correlated with intracellular accumulation of the triphosphate of TAS–106, which...

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Pubblicato in:Jpn J Cancer Res
Autori principali: Shimamoto, Yuji, Koizumi, Katsuhisa, Okabe, Hiroyuki, Kazuno, Hiromi, Murakami, Yuko, Nakagawa, Fumio, Matsuda, Akira, Sasaki, Takuma, Fukushima, Masakazu
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Publishing Ltd 2002
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5927072/
https://ncbi.nlm.nih.gov/pubmed/12149149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2002.tb01325.x
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