Ratio of Expression of p16(INK4a) to p14(ARF) Correlates with the Progression of Non‐small Cell Lung Cancer

The CDKN2 gene is located on the short arm of chromosome 9p and encodes two unrelated proteins, p16(INK4a) and p14(ARF), through the use of independent first exons and shared exons 2 and 3. p16(INK4a) is a cyclin‐dependent kinase inhibitor, whereas p14(ARF) regulates the cell cycle through a p53 and...

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Vydáno v:Jpn J Cancer Res
Hlavní autoři: Moriyama, Satoru, Nakashima, Yoshiaki, Yano, Motoki, Kaji, Masahiro, Yamakawa, Yosuke, Toyama, Tatsuya, Yamashita, Hiroko, Iwase, Hirotaka, Sasaki, Hidefumi, Saito, Yushi, Kiriyama, Masanobu, Kato, Jyoji, Fujii, Yoshitaka
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Publishing Ltd 2002
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5927070/
https://ncbi.nlm.nih.gov/pubmed/12149144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2002.tb01320.x
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